Systemic Lupus Erythematosus | Autoimmune Disease

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The most common type of lupus is Systemic Lupus Erythematosus (eh-RITH-eh-muh-TOE-sus)

It is often called SLE, or simply lupus. SLE is a chronic autoimmune disease and can range from mild to severe, with a range of effects on the body. When people talk about lupus, they are usually referring to SLE, but there are other types of lupus: Cutaneous Lupus Erythematosus, Drug-Induced Lupus, and Neonatal Lupus.

What is going on in a body with lupus?

In a properly functioning immune system, the body identifies foreign substances (such as viruses, bacteria, and germs) and creates antibodies to fight them off. With SLE and other autoimmune diseases, a body’s immune system mistakenly attacks healthy tissue, creating autoantibodies. “Auto” means self, so “autoantibodies” means that these antibodies attack the body’s own healthy cells and tissues, breaking them down and causing inflammation, damage, and pain.

SLE is a chronic disease, meaning that symptoms flare up (get worse) and then go into remission (get better). For most people, when symptoms flare up, they tend to last longer than six weeks. But because every person’s SLE is different, is important to know that everyone’s flare ups are different too. Most people with SLE will have periods of time when they feel fine (symptoms may even seem to disappear) and then periods when their disease is more active and symptoms are more severe.


The symptoms of lupus

The “systemic” part of Systemic Lupus Erythematosus means that the disease can affect many parts of the body. Although not every symptom needs to be present in order for someone to have SLE. Some of the most common symptoms of SLE are:

    • Extreme fatigue (tiredness)
    • Headaches
    • Joint pain
    • Swelling joints
    • Fever
    • Anemia (low numbers of red blood cells or hemoglobin, or low total blood volume)
    • Pain in chest on deep breathing (pleurisy)
    • Butterfly-shaped rash across cheeks and nose
    • Sun- or light-sensitivity (photosensitivity)
    • Hair loss
    • Blood clotting problems
    • Fingers turning white and/or blue when cold (Raynaud’s phenomenon)

SLE is not preventable with vaccines or curable with medications or treatment. The outlook for each individual depends a lot on the severity of lupus and when they begin to receive care. With increasing research and modern treatments in the last few decades, 80-90% of people with SLE live to the normal life expectancy. Getting appropriate medical care, following treatments and medications as directed, and living a healthy lifestyle are all crucial parts of living well with SLE.

SLE is not contagious or infectious, meaning you cannot “catch it” from someone. It is not a form of cancer and it is not like or related to HIV (Human Immunodeficiency Virus) or AIDS (Acquired Immune Deficiency Syndrome).

Lupus mostly affects women from 15 years old to 44 years old. However, men, children and teenagers can develop it, too. People of all races and ethnic groups can develop lupus, however women of color are 2-3 times more likely to develop SLE than white women.

Comments (11)

11 thoughts on “Systemic Lupus Erythematosus | Autoimmune Disease

  1. Why is it the majority of the people who have Lupus also have problems with their teeth. For example the loss of enamel on their teeth which then in turn make your teeth crack. Also with rheumatoid arthritis did your and your bones and also receding gum lines. There’s got to be a connection because there are thousands of people that are going through this. I don’t want to hear about medications because I personally and taken as minimal medication as possible which is only Xanax and dilaudid. Not on a daily basis sometimes not even on a weekly basis. Because of this issue this should be covered medically too many people walking around with no teeth. I’m not a bad-looking 54 year old woman however I refuse to engage in a relationship because of the embarrassment of my cheap. Currently using crazy glue to keep them from breaking because I can’t afford to go to a dentist because there’s no sympathetic or empathy on any Dental office all it is is about the almighty dollar. Money up front. Sickening

    1. Not sure where your from, but in MI there’s a dental school that will work on your teeth for little to no money. You can always catch a case, they will fix your teeth in prison oh, I’m not saying go that route but it’s an option LOL. I have SLE and have Mastiff problems with my gums and teeth. I believe you when you say that they are related

    2. I know what your saying. I am 32 I have lost all my teeth except for 7 bottom teeth. Before diagnosis I have no reason why my teeth were so bad. Took normal care of my teeth then all of a sudden when I was 25 they just started cracking and deteriorating. They have to be linked.

  2. I also have Sjogrens;This gives me Dry Mouth and awful teeth. It is also an autoimmune Syndrome. I have this in combination with APS and Lupus and RA.

  3. Can this be related to having blood clots? The last episode was just a week ago,and my son had blood clot in both legs as well as both of his lungs. He’s only 38 yrs old

  4. I also have daily fatigue which was made worse with trying several anti-depressants . They just made me so I couldn’t get off the couch. I don’t take any now. I am 74 years old and was diagnosed 10 years ago, but up until 3 years ago didn’t have many symptoms. The latest one being hair loss. My daughter created an oil with all natural ingredients that I am trying now. I considered trying Rogaine for women but not sure? Any help would be appreciated.

  5. I’m 47year old woman I was diagnosed with lupus 2year ago and on top of that I’m diabetic and have under active thyroid at time I get so tired I don’t even want to woke up dealing with all this is very stressful and I’m not coping pls help

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